MLLMCelltype

mLLMCelltype is an open source tool for annotating cell types in single cell RNA sequencing data. Instead of relying on one model, it sends the data to several large language models and combines their answers into a consensus, with configurable thresholds and discussion rounds to resolve disagreements between models. It is aimed at bioinformaticians and biology researchers who want automated cell type identification. The web platform needs no installation and walks through four steps: upload data, configure, process and review results. It accepts CSV, TSV and Excel files, and a sample file is available to download. Users select species and tissue, choose models from supported providers, and supply their own API keys, which can be imported from an environment file and tested before a run. Advanced options include a consensus threshold, an entropy threshold and a maximum number of discussion rounds. The site lists the tool as free and publishes no paid plans. Because it calls third party model providers using the user's own keys, any model usage charges come from those providers rather than from the tool.