Cradle

Cradle is a protein engineering platform that uses machine learning, guided by a customer's own experimental data, to generate and improve protein candidates. Scientists upload sequences and assay results, the models propose new variants, and each round of wet lab data is fed back so that the models learn as the project progresses. The platform optimizes several properties at once, including activity, binding, stability and expression, and supports antibodies, enzymes, vaccines and peptides. It is built for R&D teams in biopharma and industrial biotech, from therapeutics and vaccine developers to enzyme and food ingredient producers, with academic institutions also served. Capabilities that matter include round based project tracking from candidate generation through experimental validation, data management and reports, a beta feature for running internally developed predictors inside Cradle, fully managed AI infrastructure with no maintenance for the customer, single sign on with Google and Microsoft, SOC 2 compliance and isolation of proprietary data. Published partnerships in 2026 include Lundbeck, for brain disorder treatments, and Novonesis. Pricing is a software subscription with no royalties on resulting molecules. Amounts are not published; teams contact the company for a quote.