Persist AI

Persist AI combines machine learning with a robotic formulation lab for high throughput pharmaceutical formulation development. Its software is described as formulation AI that can be deployed in a customer's own cloud, trained on data from the company's lab. A user starts a new formulation project by choosing a dosage form, entering a drug codename, drug load and SMILES string, and selecting what to optimize for, such as solubility or stability. The system then parses the molecule, matches precedents in its knowledge base, screens excipients and risks, and compiles a formulation report. Reports cover the API profile, formulation and critical material attributes, critical process parameters, packaging and analytical considerations, and distinguish items grounded in literature or databases from computational predictions that need experimental validation. Users can log their own lab observations to the knowledge base so the model improves with their results. Supported forms include amorphous solid dispersions, SEDDS and SMEDDS, immediate release and orally disintegrating tablets, topicals and injectables. The company also works on long acting injectables, parenterals, creams and in situ depots, and publishes screening studies such as PLGA microsphere work. It is intended for pharmaceutical and biotech formulation scientists who want to reach a quality target product profile faster. Pricing is not published on the site. Visitors are directed to get in touch.